Friday, December 16, 2011

0 Science Article: Oral Bacteria Opens Door To Allow Pathogens In

In today's Science Daily, there is an article on a study showing how one specific oral bacteria, Fusobacterium nucleatum, can provide a gateway for other bacteria to enter human blood vessels and make people sick.

READ MORE Here: http://www.sciencedaily.com/releases/2011/12/111215113521.htm

Original Source:
Yann Fardini, Xiaowei Wang, Stéphanie Témoin, Stanley Nithianantham, David Lee, Menachem Shoham, Yiping W. Han. Fusobacterium nucleatum adhesin FadA binds vascular endothelial cadherin and alters endothelial integrity. Molecular Microbiology, 2011; 82 (6): 1468 DOI: 10.1111/j.1365-2958.2011.07905.x

Reading this reminded me of an earlier post and comments I made about a paper by Judith Miklossy: Alzheimer's disease - a neurospirochetosis.

In my comments there, I stated:

"I think it's possible that infection can be part of the precursor or a cascade effect that gets the ball rolling towards Alzheimer's Disease (AD) - but the question remains: Why do plenty of people have Bb or HSV-1 or any of a number of infections who do not develop AD?"

Maybe this is what makes the difference. Maybe Fusobacterium nucleatum has to cross the endothelium and open the gate for bacteria such as Bb or oral Treponema to cross the blood-brain barrier. If Fusobacterium nucleatum can travel to the brain first, then perhaps these other bacteria will follow on its heels and lead to neurological damage.

It seems further studies to seek Fusobacterium nucleatum in brain biopsies alongside other bacteria could provide some evidence that this is what has happened.

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